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What we'll learn from Anthropic's $2-$3T IPO | E2325

This Week in Startups

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This Week In Startups is made possible by: PayPal Open https://paypalopen.com [https://paypalopen.com] CLA https://claconnect.com/withyou [https://claconnect.com/withyou] Odoo https://Odoo.com/twist [https://odoo.com/twist] Today's show: *Anthropic is likely headed for the largest IPO in history. A reported 2-3 trillion October debut would blow past SpaceX's recent record. Jason breaks down why the. numbers matter less than what they'll reveal about the entire AI economy. Then, chats with a pair of founders: one who's selling subscription water filtration systems that will keep microplastics out of your brain (and other body parts), and another who's building the AI software that powers automated solar panel installation. Guests Sami Khoreibi: https://x.com/samikhoreibi [https://x.com/samikhoreibi] Wisewell: https://www.wisewell.com/ [https://www.wisewell.com/] Puneet Puri: https://x.com/puneetp [https://x.com/puneetp] Gritt Robotics: https://www.gritt.ai/ [https://www.gritt.ai/] Relevant Links Fortune: Anthropic reportedly plans $2T IPO in October: https://fortune.com/2026/08/13/anthropic-ipo-2-trillion-october-largest-ever-spacex/ [https://fortune.com/2026/08/13/anthropic-ipo-2-trillion-october-largest-ever-spacex/] Ramp AI Index: August update: https://ramp.com/data/ai-index-august-2026 [https://ramp.com/data/ai-index-august-2026] Decart: https://decart.ai/ [https://decart.ai/] Bloomberg: Anthropic in talks to buy Decart: https://www.bloomberg.com/news/articles/2026-08-13/anthropic-said-in-talks-to-buy-ai-startup-decart-for-6-billion [https://www.bloomberg.com/news/articles/2026-08-13/anthropic-said-in-talks-to-buy-ai-startup-decart-for-6-billion] Nat Geo: Profile of water sommelier Martin Riese: https://www.nationalgeographic.com/travel/article/water-sommelier-martin-riese [https://www.nationalgeographic.com/travel/article/water-sommelier-martin-riese] Mailman School of Public Health: Nanoplastics study: https://www.publichealth.columbia.edu/news/bottled-water-can-contain-hundreds-thousands-nanoplastics [https://www.publichealth.columbia.edu/news/bottled-water-can-contain-hundreds-thousands-nanoplastics] Bryan Johnson microplastics post: https://x.com/bryan_johnson/status/1937194358027190637?lang=en [https://x.com/bryan_johnson/status/1937194358027190637?lang=en] Topo Chico: https://www.coca-cola.com/us/en/brands/topo-chico [https://www.coca-cola.com/us/en/brands/topo-chico] San Pellegrino: https://www.sanpellegrino.com/ [https://www.sanpellegrino.com/] Acqua Panna: https://www.acquapanna.com/intl/ [https://www.acquapanna.com/intl/] Evian: https://www.evian.com/ [https://www.evian.com/] Mountain Valley Spring Water: https://mountainvalleyspring.com [https://mountainvalleyspring.com] Fiji Water: https://www.fijiwater.com/ [https://www.fijiwater.com/] TechCrunch: Gritt exits stealth: https://techcrunch.com/2026/07/21/gritt-exits-stealth-with-34-million-for-robots-to-build-solar-plants-then-everything-else/ [https://techcrunch.com/2026/07/21/gritt-exits-stealth-with-34-million-for-robots-to-build-solar-plants-then-everything-else/] Our World in Data: Solar panel prices: https://ourworldindata.org/grapher/solar-pv-prices [https://ourworldindata.org/grapher/solar-pv-prices] Our World in Data: Solar module prices vs. cumulative capacity: https://ourworldindata.org/grapher/solar-pv-prices-vs-cumulative-capacity [https://ourworldindata.org/grapher/solar-pv-prices-vs-cumulative-capacity] NYT: Do your emojis make you look old? https://www.nytimes.com/interactive/2026/08/12/upshot/emoji-generations.html [https://www.nytimes.com/interactive/2026/08/12/upshot/emoji-generations.html] DJI Mic 3: https://www.dji.com/mic-3 [https://www.dji.com/mic-3] Ted Lasso S4 trailer: https://www.youtube.com/watch?v=Kk1KdTMhFs8 [https://www.youtube.com/watch?v=Kk1KdTMhFs8] Lanterns trailer: https://www.youtube.com/watch?v=7UIBOsuUwc4 [https://www.youtube.com/watch?v=7UIBOsuUwc4] Furious trailer: https://www.youtube.com/watch?v=UBSqPDxmNZs [https://www.youtube.com/watch?v=UBSqPDxmNZs] The Shards trailer: https://www.youtube.com/watch?v=Zpm9HUOrZIc [https://www.youtube.com/watch?v=Zpm9HUOrZIc] Sporked: What are Tim Tams? https://sporked.com/article/what-are-tim-tams/ [https://sporked.com/article/what-are-tim-tams/] Timestamps: 0:00 New Segment: "Enough Already!" 3:36 Anthropic's record-breaking IPO plans 9:59 Why it's "Springtime for Trump and M&A" 10:39 PayPal - Built for payments, growth, and agentic. Paypal Open, built for all business. Visit https://paypalopen.com to get started 16:00 Sami Khoreibi of Wisewell joins 17:30 Hiring a water sommelier 20:23 CLA - Innovation takes balance. CLA's CPAs, consultants, and wealth advisors can help you get from startup to where you want to end up. Get started now at https://www.claconnect.com/withyou 29:00 The problems with tap and bottled water 30:34 Odoo - The all-in-one business platform. Get started for free at https://Odoo.com/twist 49:58 Puneet Puri of Gritt Robotics joins 54:35 Solar's version of "Moore's Law" 1:05:08 Are you using the Boomer emojis? 1:09:02 Why Jason loves the DJI Mic 3 1:11:36 Jason & Lon's streaming recommendations Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com [https://ticker.thisweekinstartups.com] Check out the TWIST500: https://www.twist500.com [https://www.twist500.com] Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp [https://rb.gy/v19fcp] Follow Lon: X: https://x.com/lons [https://x.com/lons] Follow Jason: X: https://twitter.com/Jason [https://twitter.com/Jason] LinkedIn: https://www.linkedin.com/in/jasoncalacanis [https://www.linkedin.com/in/jasoncalacanis] Check out all our partner offers: https://partners.launch.co/ [https://partners.launch.co/] Great TWIST interviews: Will Guidara, [https://youtu.be/pvJa2pzuXWQ] Eoghan McCabe [https://youtu.be/9dHN4YFkgv4], Steve Huffman [https://podcasts.apple.com/us/podcast/reddit-ceo-steve-huffman-on-mod-revolt-building-a/id315114957?i=1000617333424], Brian Chesky [https://podcasts.apple.com/ca/podcast/airbnb-ceo-brian-chesky-on-early-rejection-customer/id315114957?i=1000611761112], Bob Moesta, [https://youtu.be/y2UMzSqX94Q] Aaron Levie [https://podcasts.apple.com/ca/podcast/box-ceo-aaron-levie-breaks-down-box-ai-and-generative/id315114957?i=1000612384545], Sophia Amoruso [https://podcasts.apple.com/ca/podcast/sophia-amoruso-on-branding-raising-a-fund-portfolio/id315114957?i=1000601352978], Reid Hoffman [https://podcasts.apple.com/ca/podcast/reid-hoffman-on-ais-crescendo-moment-regulation-and/id315114957?i=1000612548498], Frank Slootman [https://podcasts.apple.com/ca/podcast/snowflake-ceo-frank-slootman-on-moving-the-needle-win/id315114957?i=1000602560622], Billy McFarland [https://podcasts.apple.com/ca/podcast/billy-mcfarland-on-fyre-fest-fraud-failure-hacking/id315114957?i=1000610922577] Check out Jason's suite of newsletters: https://substack.com/@calacanis [https://substack.com/@calacanis] Follow TWiST: Twitter: https://twitter.com/TWiStartups [https://twitter.com/TWiStartups] YouTube: https://www.youtube.com/thisweekin [https://www.youtube.com/thisweekin] Instagram: https://www.instagram.com/thisweekinstartups [https://www.instagram.com/thisweekinstartups] TikTok: https://www.tiktok.com/@thisweekinstartups [https://www.tiktok.com/@thisweekinstartups] Substack: https://twistartups.substack.com [https://twistartups.substack.com]

Highlights

This episode examines major shifts in technology, consumer services, and automation, balancing market analysis with conversations about practical startup innovation.
00:00
AI is being embedded everywhere, whether needed or not
09:07
Public stock can fuel strategic acquisitions
10:01
M&A signals springtime for venture capital
10:39
A few successful deals can create enormous value
16:00
Early GLP-1 weight loss can be remarkably rapid.
17:30
Cleaner water tastes better with balanced minerals
28:36
Retention turns water filtration into a utility-like service.
29:04
Regional water shapes local flavor
35:41
Microplastics raise questions about long-term exposure
53:00
AI could quadruple solar installation productivity
54:35
Automation is essential for scaling solar installation.
1:05:09
Emoji choices signal generational identity
1:19:25
The best period shows hide history in the details.

Chapters

New Segment: "Enough Already!"
00:00
Anthropic's record-breaking IPO plans
03:36
Why it's "Springtime for Trump and M&A"
09:59
PayPal - Built for payments, growth, and agentic. Paypal Open, built for all business. Visit https://paypalopen.com to get started
10:39
Sami Khoreibi of Wisewell joins
16:00
Hiring a water sommelier
17:30
CLA - Innovation takes balance. CLA's CPAs, consultants, and wealth advisors can help you get from startup to where you want to end up. Get started now at https://www.claconnect.com/withyou
20:23
The problems with tap and bottled water
29:00
Odoo - The all-in-one business platform. Get started for free at https://Odoo.com/twist
30:34
Puneet Puri of Gritt Robotics joins
49:58
Solar's version of "Moore's Law"
54:35
Are you using the Boomer emojis?
1:05:08
Why Jason loves the DJI Mic 3
1:09:02
Jason & Lon's streaming recommendations
1:11:36

Transcript

Jason Calacanis: All right, everybody, it's TWiST. It's Friday, August 14th. Lon Harris is here. Follow him at @lons on Twitter. Hear his media recommendations. And Trump derangement syndrome. Just plenty of stuff there for you. And you can follow me on th...