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WORLD’S TOP OBGYN Dr. Aliabadi: The #1 Hormone Problem Affecting Millions of Women (And The 4 Changes That Can Reverse It)

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WORLD’S TOP OBGYN Dr. Aliabadi: The #1 Hormone Problem Affecting Millions of Women (And The 4 Changes That Can Reverse It)

On Purpose with Jay Shetty

Mar 11
On Purpose with Jay Shetty

On Purpose with Jay Shetty

Mar 11
OverviewShownoteHighlightsTranscriptChaptersPins

Shownote

For many women, the real challenge isn’t just unexplained health problems, it’s being heard when they seek help. Jay sits down with Dr. Thaïs Aliabadi, or "Dr. A", to unpack a silent crisis affecting millions of women around the world: undiagnosed PCOS an...

Highlights

This episode centers on the urgent, often invisible struggles women face with PCOS and endometriosis—conditions that extend far beyond fertility to impact mental health, metabolism, and daily quality of life.
00:00
75% of women with PCOS and over 90% with endometriosis are undiagnosed
03:04
Millions of women can't achieve a calm state due to underlying conditions like PCOS and endometriosis
04:04
PCOS is a chronic, hormonal, metabolic, inflammatory, and neurological condition affecting 15%–20% of women, with 75% remaining undiagnosed
07:13
PCOS diagnosis requires meeting two of three criteria: irregular periods, PCOS-looking ovaries on ultrasound (or high egg count/AMH), and elevated testosterone/androgen symptoms
09:20
The first 'domino' in PCOS is insulin resistance, which occurs when PCOS patients' cells don't respond properly to insulin after eating carbohydrates
18:47
Ovii supplement with wild mulberry leaf blocks 40% of carbohydrate absorption when taken before the heaviest meal
19:41
Lowering insulin can lead to more regular ovulation and reduced inflammation
22:21
A friend's call shifted Jay's perspective on human connection
28:40
Chronically elevated LH stimulates ovarian androgen production, blocking ovulation and perpetuating PCOS symptoms
29:29
Chronic inflammation worsens insulin resistance, increases androgen secretion, and affects mental health in PCOS
31:26
PCOS causes limbic system dysfunction leading to anxiety, depression, brain fog, and food cravings
35:03
Prescribing birth control pills only masks PCOS symptoms, not addressing inflammation, insulin resistance, and neurological effects
43:05
Endometriosis is not just a pelvic or fertility issue but also affects the central nervous system
46:12
Endometriosis is a clinical diagnosis and patients can self-diagnose based on symptoms like debilitating period pain, painful sex, and chronic inflammation
49:22
Diagnosing endometriosis with over 90% accuracy takes about five minutes
56:10
Many gynecologists miss endometriosis implants because they are small, purple, glandular, and inflammatory, requiring an experienced laparoscopic surgeon to identify them
57:53
Over 50% of PCOS patients also have endometriosis
1:00:35
Endometriosis causes pain, anxiety, depression, and fertility issues
1:07:42
90% of endometriosis patients have leaky gut and SIBO, driving inflammation and systemic symptoms
1:27:13
Many cases of unexplained infertility are due to endometriosis, PCOS, or autoimmune conditions, and early intervention could reduce the need for fertility centers.

Chapters

Intro
00:00
Are We Facing a Fertility Crisis?
02:58
What Is PCOS?
03:58
Why PCOS Often Goes Undiagnosed
07:13
The Impact of Insulin Resistance
09:15
Making PCOS Patients Insulin-Sensitive
15:06
The Nutritional Effects of GLP-1 Medications
19:37
High Androgens and Chronic Inflammation
22:14
How Hormonal Imbalances Affect the Brain
25:39
Why Birth Control Alone Isn’t Enough
29:25
How to Know If You Have PCOS
31:23
Painful Periods Are Not Normal
35:01
What Is Endometriosis?
36:47
The Most Effective Treatment Approach for Endometriosis
46:07
The Risks of Ignoring Endometriosis
49:20
How to Use Birth Control Strategically
53:09
What to Do If Egg Freezing Isn’t an Option
56:04
The Link Between Endometriosis and Leaky Gut
57:53
Potential IVF Complications Explained
1:00:33
A Scientific Approach to Infertility
1:04:38
What to Do If You’re Not Getting Pregnant
1:10:01

Transcript

Jay Shetty: This is an iHeart Podcast, guaranteed human. Sometimes you just need to go to your happy place. And there's no better happy place than celebrity cruises. They get you closer than close to the history, culture and flavors of Europe. And now they...