How Andrew Wilkinson Uses Opus 4.5 in His Work and Life
AI & I
Jan 21
How Andrew Wilkinson Uses Opus 4.5 in His Work and Life
How Andrew Wilkinson Uses Opus 4.5 in His Work and Life

AI & I
Jan 21
Shownote
Shownote
Entrepreneur Andrew Wilkinson used to sleep nine hours a night. Now he wakes up at 4 a.m. and goes straight to work—because he can’t wait to keep building with Anthropic’s latest model, Opus 4.5. Two years ago, Wilkinson was obsessed with vibe coding on ...
Highlights
Highlights
In this episode, entrepreneur Andrew Wilkinson shares how cutting-edge AI tools like Claude Code and Opus 4.5 are transforming not only software development but also personal decision-making and business strategy. His journey from skepticism to full immersion reveals a new era where AI doesn't just assist but actively drives innovation.
Chapters
Chapters
Start
00:00Introduction
01:07Why Opus 4.5 feels like the iPhone moment for vibe coding
02:48Why designers have a unique advantage with AI
08:31How Wilkinson built a custom email client with Claude Code
14:10An AI trained on your relationship that predicts your fights
18:13Using AI meeting notes to make your life better
30:40Don't inject your opinion into prompts
35:11Wilkinson’s Claude Code tips and workflows
40:21Your personal stylist is a prompt away
47:59How AI is changing the way Wilkinson invests in software
53:17Transcript
Transcript
Andrew Wilkinson: Over the last two weeks, I've been playing with Claude Code and Opus 4.5 and I am just blown away. It literally feels like I have like 30 free employees and they're just working 24-7 and I'm paying them like $40 a day. It's crazy. It's al...