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#2421 - Derek, More Plates More Dates

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#2421 - Derek, More Plates More Dates

The Joe Rogan Experience

2025/12/02
The Joe Rogan Experience

The Joe Rogan Experience

2025/12/02
OverviewShownoteHighlightsTranscriptChaptersPins

Shownote

Derek is the fitness educator and entrepreneur behind the "More Plates, More Dates" YouTube channel, podcast, and companion website.www.moreplatesmoredates.com www.youtube.com/@MorePlatesMoreDates Perplexity: Download the app or ask Perplexity anything...

Highlights

This episode dives into the science and culture behind cognitive enhancement, athletic performance, and the evolving landscape of health optimization. From nootropics and hormone therapy to the realities of elite combat sports and the psychological toll of fame, the conversation spans cutting-edge biohacking and the human stories behind physical transformation.
02:45
Uridine Monophosphate enhances sensitivity to stimulants and may have neuroprotective effects
11:06
A failed Gorilla Mind prototype caused nausea due to dopamine overdose from velvet bean extract
16:05
Caffeine’s efficacious dose for performance is 500–600 mg or 3–6 mg/kg
21:40
Creatine can offset performance deterioration in ATP production and resource pulling
28:36
Bodybuilders who lied about steroid use lost credibility when exposed
31:04
Frank Guerrillo openly shares his TRT protocol and its positive impact on performance, sleep, and mood.
40:29
Dave Bautista bulked up significantly for movie roles like Glass Onion.
44:50
Stand-up is now the most unrestrained form of comedy.
49:37
'Slow Horses' is a standout Apple TV show with Gary Oldman as a disgraced MI5 agent.
54:45
McLaren refuses to favor its leading driver, opening the door for a Red Bull victory.
57:20
Glycerol enables hyperhydration without frequent urination
1:04:53
FDA removes black box warnings on bioidentical HRT, correcting past misinformation based on synthetic hormone studies.
1:07:27
Not taking bioidentical hormones can deteriorate women's health due to lack of cardioprotective and neuroprotective support
1:18:35
Lionel Messi was supplied with growth hormone to reach an acceptable adult height and become a great football player.
1:31:26
A 25-year-old fighter trains with Jon Jones and displays effortless athleticism, including leaping over ropes.
1:33:45
Pereira's punching power registered at 190 on a punching machine, significantly higher than Francis Ngannou's 129.
1:42:06
Ilya dominated Charles Oliveira with superior mechanics and timing
1:48:59
Seeking attention on social media is dangerous and bad for mental health
2:28:27
Inspiring video of a kid going from out of shape to completing an Iron Man in 100 days

Chapters

What’s really in that red gummy brain booster?
00:00
How do you build a smarter cognitive stack?
06:00
Is caffeine still the ultimate legal performance aid?
13:35
Why starting low matters when taking supplements
18:57
Remember when stores sold steroid-like pills openly?
24:02
Why telling the truth about TRT builds credibility
31:04
When does a Hollywood body transformation raise red flags?
38:29
How far should actors go for a role—and why?
42:33
Which new shows are worth your streaming time?
47:14
Can team politics decide an F1 championship?
52:01
Do F1 drivers rely on nootropics to stay sharp?
57:20
How one man healed his Achilles with stem cells
1:02:18
Why were bioidentical hormones misunderstood for decades?
1:07:27
What happens when women get too much testosterone?
1:13:09
Did growth hormone shape Messi’s legendary career?
1:18:35
How did Yoel Romero become an MMA anomaly?
1:23:44
Just how powerful is Pereira’s punch—really?
1:33:45
Could changing weight classes reshape a fighter’s future?
1:39:28
Why can divorce go viral—and ruin lives?
1:46:38
Is quitting social media the ultimate act of focus?
1:51:25
Who’s selling brain boosters and health checkups at the end?
2:51:03

Transcript

Speaker 3: The Joe Rogan Experience. Train by day, Joe Rogan podcast by night, all day. Joe Rogan: New drink. Look at this here. Red gummy fish. I'm about to try it for the first time. And this is a nootropic? Derek: Yeah, so it's, I think on the first e...