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Core Memory

Ashlee Vance

Core Memory

Ashlee Vance

Core Memory is a podcast about science and technology hosted by best-selling author and filmmaker Ashlee Vance. Vance has spent the past two decades chronicling advances in science and tech for publications like The Economist, The New York Times and Bloomberg Businessweek. Along with the stories, he's written best-selling books like Elon Musk’s biography, made an Emmy-nominated tech TV show watched by millions and produced films for HBO and Netflix. The goal has always been to bring the tales of complex technology and compelling people to the public and give them a path into exceptional and unusual worlds they would not normally have a chance to experience. www.corememory.com [https://www.corememory.com?utm_medium=podcast]

3 DAYS AGO

AI Ready

The Great Reset At OpenAI — EP 67 Sam Altman And Greg Brockman

Sam Altman and Greg Brockman came on Core Memory together for a ten-year look back at OpenAI. It’s also the first time they’ve done a media podcast together. We juiced every second of our 90 minutes with the cofounders of OpenAI. We got into the company r...

The Great Reset At OpenAI — EP 67 Sam Altman And Greg Brockman

Apr 16

The $50,000 Underwater Drone - EP 66 Ulysses

Guinness. Sharks. American manufacturing. These are a few of the interests I share with the founders of Ulysses, a San Francisco startup building autonomous underwater drones. The idea for Ulysses started when one of the four co-founders was on a surf tri...

The $50,000 Underwater Drone - EP 66 Ulysses

Apr 15

The Very Wild, Very Real Plan To Build AI Data Centers In The Ocean - EP 65 Garth Sheldon-Coulson

We’re in a moment of insatiable desire for more energy and more computing. And so the ideas of how to provide said energy and computing are getting ever more adventurous. Case in point: Panthalassa, which is the subject of this week’s episode, alongside o...

The Very Wild, Very Real Plan To Build AI Data Centers In The Ocean - EP 65 Garth Sheldon-Coulson

Apr 08

The Company Helping Paralyzed People Move And Thrive Again - EP 64 Dave Marver

Three years ago, I’d caught some videos online of paralyzed people walking again. This struck me as miraculous. It also confused me. If paralyzed people were moving again, why weren’t more people talking about this incredible occurrence? The company helpi...

The Company Helping Paralyzed People Move And Thrive Again - EP 64 Dave Marver

Apr 01

He Hacked Finance And Is Now Building An AI CEO - EP 63 Pedro Franceschi

Pedro Franceschi taught himself to code when he was eight years old. At 12, he began receiving legal notices from Apple, asking him to stop hacking iPhones. By 14, he was making hundreds of thousands of dollars a year selling software and had his mom accom...

He Hacked Finance And Is Now Building An AI CEO - EP 63 Pedro Franceschi

Mar 25

Here Come The Space Lasers - EP 62 Baiju Bhatt

Baiju Bhatt is trying to pull an Elon Musk. About 25 years ago, Musk sold his finance tech company PayPal and left dot-com life to get into rockets with the founding of SpaceX. Hardly anyone considered this a rational choice on Musk’s part. Space, after a...

Here Come The Space Lasers - EP 62 Baiju Bhatt

Mar 18

The Aussie Man Who Used AI To Create A Cancer Cure For His Dog

We have tracked down the man and dog of the hour. Paul Conyngham and his dog Rosie gained worldwide attention over the past week for breaking new medical ground. Using a variety of artificial intelligence tools, Conyngham – and some doctors and scientists...

The Aussie Man Who Used AI To Create A Cancer Cure For His Dog

Mar 11

Inside The Race To Reboot Human Cells - EP 60 Nabiha Saklayen

The mainstream media says almost nothing about induced pluripotent stem cells (iPSCs). So, you’re lucky that we’re here to help. These cells with a clunky name hold the promise of being able to reverse the aging process across our bodies. Put rather blunt...

Inside The Race To Reboot Human Cells - EP 60 Nabiha Saklayen

Mar 04

He Thinks AI Code May Break Everything - EP 59 Will Wilson

Will Wilson paints a bleak picture for where we’re heading with code written by AIs. He thinks the world will fill with poorly written code that no one understands and that software bugs will proliferate through critical systems. Your airplane that has go...

He Thinks AI Code May Break Everything - EP 59 Will Wilson

Feb 25

She Survived Being Shot, Bombed And Working At Google - EP 58 Anna Prouse

Anna Prouse has survived multiple assassination attempts. She’s been tapped by General David Petraeus to get work done in Iraq that U.S. troops couldn’t handle. She’s faced off against Iranian militants. Over a multi-decade career working in the Middle Eas...

She Survived Being Shot, Bombed And Working At Google - EP 58 Anna Prouse

Feb 19

The Grand Quest To Simulate Life - EP 57 Ed Boyden

Ed Boyden has spent the last twenty or so years building the technology needed to create a working simulation of living systems. Put another way – he’s been trying to turn biology into physics. Boyden has helped develop new techniques for imaging the brai...

The Grand Quest To Simulate Life - EP 57 Ed Boyden

Feb 11

What's Real And What's Fake In Tech - EP 56 Peter Barrett

We do not usually do venture capitalists on the Core Memory podcast. They can be a lot and like to hear themselves talk a bit too much. (Not you! The other ones – Ed.) But, for Peter Barrett, we will always make an exception. He’s a general partner at Pla...

What's Real And What's Fake In Tech - EP 56 Peter Barrett

Feb 04

The Joy And Doom Of New San Francisco - EP 55 Jayden Clark

The center of the universe has been born again. The most insufferable posters on our timeline, including myself, are enjoying the abundance found in San Francisco thanks to the AI boom lining the pockets of fresh college dropouts. The themed parties are bu...

The Joy And Doom Of New San Francisco - EP 55 Jayden Clark

Jan 28

The Present And Future Of Gene Editing - EP 54 Jennifer Doudna

Let’s get right to the point: Nobel Prize winner Jennifer Doudna is on the pod this week. Doudna won the 2020 Nobel Prize in Chemistry alongside Emmanuelle Charpentier for their work developing “a method for high-precision genome editing.” They, and other...

The Present And Future Of Gene Editing - EP 54 Jennifer Doudna

Jan 22

He Left OpenAI To Think Bigger - EP 53 Jerry Tworek

On January 5th, famed AI researcher Jerry Tworek stunned world+dog by announcing his departure from OpenAI. A few days later, he hopped over to the Core Memory podcast studio for his not-so-formal exit interview. Tworek joined OpenAI in 2019 when the rese...

He Left OpenAI To Think Bigger - EP 53 Jerry Tworek

Jan 14

Welcome To The Chinese Peptide Underground - EP 52 Jasmine Sun

Biohacking has gone through a lot of different phases. Implanting an NFC chip in your hand is old school and having a blood boy is passé. Among Silicon Valley’s 20-somethings, all the cool kids have a peptide stack. Jasmine Sun joins us this week to chat ...

Welcome To The Chinese Peptide Underground - EP 52 Jasmine Sun

Jan 12

New, More Precise Cancer Therapies Could Soon Be Here - EP 51 Richard Fuisz

We have a guest host and some breaking news for this episode. Eryney Marrogi, the scientist and soon-to-be doctor who writes for us now and again, has taken over the pod studio to interview Richard Fuisz. Earlier today, Marrogi broke a story on Fuisz’s co...

New, More Precise Cancer Therapies Could Soon Be Here - EP 51 Richard Fuisz

2025/12/24

Is The Era Of AI-Designed Drugs Actually Here? - EP 50 Josh Meier and Jack Dent

We have been talking about computer-aided drug discovery for well more than a decade. It used to be the case that start-ups pitched their ability to use “machine learning” to hunt for new, promising therapies. Now we call machine learning “artificial intel...

Is The Era Of AI-Designed Drugs Actually Here? - EP 50 Josh Meier and Jack Dent

2025/12/17

The Next Step Toward Understanding The Nature Of Intelligence - EP 49 Sebastian Seung

Well, here we are. It’s brain uploading time. As we’ve just reported, famed neuroscientist Sebastian Seung has created a new start-up called Memazing. The company has set out to build digital brains in software that are based upon the maps of animal brain...

The Next Step Toward Understanding The Nature Of Intelligence - EP 49 Sebastian Seung

2025/12/10

Attacking Cancer With Code And Winning - EP 48 Jake Becraft

Jake Becraft was working on mRNA way before it was cool. In fact, Becraft’s advisors at MIT told him trying to develop therapies with mRNA would be a colossal waste of time. But, here we are in 2025, and Becraft has pushed the mRNA technology that gained ...

Attacking Cancer With Code And Winning - EP 48 Jake Becraft