The episode begins with Cayce's devout Christian upbringing and mystical childhood experiences, including an encounter with a winged being. At age 21, he lost his voice and, under hypnosis, diagnosed his own condition as psychological stress, leading to his recovery. This event sparked his healing abilities. Encouraged by Dr. Al Layne, Cayce began performing trance readings for others, successfully treating ailments and offering spiritual advice. Despite skepticism from the medical community, his reputation grew, and he refused to charge fees, relying on donations. He married Gertrude Evans and worked as a photographer, but financial strain followed. The episode highlights his legendary readings on health, finance, and spirituality, and the ethical challenges posed by increasing demand. The hosts also speculate on questions they would ask Cayce and discuss the supportive partnership with his wife and assistant Gladys Davis.