Ketamine, Magic Mushrooms, Ibogaine & the Truth About Depression | Dr. Amy Price Neff | Wait What?!
Earth to Aimee Mayo
Apr 23
Ketamine, Magic Mushrooms, Ibogaine & the Truth About Depression | Dr. Amy Price Neff | Wait What?!
Ketamine, Magic Mushrooms, Ibogaine & the Truth About Depression | Dr. Amy Price Neff | Wait What?!

Earth to Aimee Mayo
Apr 23
Shownote
Shownote
Ketamine therapy. Magic mushrooms. Psychedelics. Treatment resistant depression.
Matthew Perry. And a mushroom that naturally produces ketamine. This episode
covers all of it.
Dr. Amy Price Neff is a Nashville physician, founder of MindStream Integrative
Medicine, trained at the University of Virginia and University of Arizona, and
certified in psychedelic-assisted psychotherapy.
We go deep on what ketamine therapy actually feels like, how it rewires the
brain, why it works two to three times better than antidepressants for most
people, and how psilocybin mushrooms compare. We also cover what really happened
to Matthew Perry, whether mushrooms can help with grief, why cannabis is
Schedule 1 while opioids are Schedule 2, and what to say when someone you love
makes comments about not wanting to be here.
Aimee also shares something she has never said publicly before. That she
attempted suicide at 19 while on antidepressants that were later pulled from the
market because of exactly what they did to her.
This episode is for anyone who has tried everything and still feels hopeless.
For anyone who lost someone to mental illness. For anyone who is just trying to
feel better and keeps hitting a wall.
Not medical advice. Always talk to your own doctor. But this conversation might
change how you think about what healing actually looks like.
Aimee's Social's: https://linktr.ee/WaitWhatPod [https://linktr.ee/WaitWhatPod]
Highlights
Highlights
This podcast explores the potential of psychedelic therapies, particularly ketamine and psilocybin, for treating depression, grief, and other mental health conditions. The conversation delves into the science behind these treatments, their practical application, and the societal stigma surrounding them, while also addressing personal experiences and the systemic barriers to access.
Chapters
Chapters
Content Warning And Personal Context
00:00What Ketamine Is And Why
02:20Vietnam Origins And Mushroom Surprise
05:05Early Skepticism After Patient Loss
07:45Ketamine Versus Psilocybin For Mood
11:10Dosing And Routes Of Use
15:20What A Session Can Feel Like
22:40Integration And The Mind’s Metaphors
30:40Parts Work And Setting Intentions
41:30War On Drugs And Access Barriers
52:40Addiction Risk And Matthew Perry Fallout
1:03:30Who Ketamine Is Best For
1:12:40Expectations Mindset And Success Rates
1:20:40Ketogenic Diets And Metabolic Mental Health
1:22:50Group Healing And Relearning Connection
1:28:30Finding The Right Clinic And Closing
1:42:40Transcript
Transcript
Dr. Amy Price Neff: So about 60% of those after one psilocybin session really lose their fear of dying.
Aimee Mayo: I think that's one thing ketamine does is it lets you go back and change the story a little bit.
Dr. Amy Price Neff: That visual image mig...