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Insulin Doctor: This Is The First Sign Of Dementia! The Shocking Link Between Keto & Brain Decline!

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Insulin Doctor: This Is The First Sign Of Dementia! The Shocking Link Between Keto & Brain Decline!

The Diary Of A CEO with Steven Bartlett

2025/11/24
The Diary Of A CEO with Steven Bartlett

The Diary Of A CEO with Steven Bartlett

2025/11/24
OverviewShownoteHighlightsTranscriptChaptersPins

Shownote

No.1 Keto Doctor DR. ANNETTE BOSWORTH reveals how to reverse insulin resistance, cut belly fat, avoid early dementia, why eating late spikes glucose, and the sardine-only reset for ketosis. Dr Annette Bosworth, commonly known as Dr Boz, is an internal me...

Highlights

In this insightful conversation, Dr. Annette Bosworth, a seasoned internal medicine physician and leading voice in metabolic health, dives deep into the science and real-world application of ketogenic living. She shares how shifting from symptom management to root-cause healing can transform long-term wellness, particularly by mastering insulin regulation and metabolic flexibility.
01:00
Excess insulin is the root cause of most chronic diseases.
02:16
Most chronic diseases could be reversed by regularly making ketones
03:23
Chronic issues signal the body's waste exceeds its cleanup capacity
06:54
Fixing underlying chemistry leads to better long-term health and vitality
11:03
High insulin over years can lead to skin tags and brain issues
13:05
High insulin prevents the body from removing cellular waste and must be lowered for metabolic cleanup.
17:05
One can't burn fat or produce ketones until glycogen stores are empty
18:39
Skin tags in the neck, armpits, and groin can fall off when insulin levels decrease
20:42
Patients reversed grey hair on a ketogenic diet due to healthier hair-making cells
21:43
Reducing carbs to 20 grams or less helps initiate ketosis
23:21
Ketones can fuel the brain even in cases of insulin resistance
25:19
Participants in a three-week ketogenic program reported feeling great and having high energy
30:22
Exiting ketosis leads to rapid return of joint pain, brain fog, and irritability
31:18
A low-inflammation ketogenic setting enables quicker recovery from injuries.
32:38
Muscles can be trained to use fat as fuel, offering a longer-lasting energy source with less inflammation
34:24
After three weeks on keto, a girl with Down syndrome and Alzheimer's said her first three-syllable word.
38:40
Blood sugar below triple digits and ketone levels above 0.5 indicate successful ketosis
41:09
Late-night eating causes high insulin production and disrupts fat-burning.
42:39
Late-night eating impairs metabolism and memory due to prolonged digestive activity and hormonal shifts.
43:41
Jack's blood sugar is 88 with a ketone level of 0.1, yielding a high Dr. Boz Ratio
45:13
Low ketone levels (0.1 - 0.3) indicate glucose dependency due to high insulin and cortisol
46:32
One son at Georgetown Law School finds he can't focus without being in ketosis.
50:05
A 36-hour fast may be necessary for metabolic reset in those with long-term high insulin levels.
54:23
A ketogenic state allows mitochondria to use both ketones and glucose.
54:49
Sardines in oil can trigger ketone production within 48-72 hours for those stuck in high insulin states.
57:31
High ketone levels mean you're burning fat efficiently with low insulin interference.
58:07
Net carbs are calculated by subtracting fiber from total carbs
59:25
Patients with high insulin can't follow a certain way
1:02:21
I've never had the best day of my life — but now I feel free to look for it.
1:05:44
Butyrate, not fiber, is essential for producing gut hormones like GLP-1 that affect brain health
1:06:59
Eating only one thing won't lead to a diverse gut microbiome
1:07:36
High insulin levels block Vitamin D from reaching cells
1:08:33
Jane's Vitamin D level increased to 108 while insulin decreased during the Sardines Challenge.
1:10:44
Most people are deficient in magnesium due to depleted soils and modern diets.
1:11:43
Omega-3 recommended for those not eating fish
1:11:58
Exogenous means externally consumed, not produced by the body.
1:12:34
Ketones appear in the blood quickly and stimulate liver ketone production for 12 hours, which is beneficial for cancer patients undergoing chemo or radiation.
1:17:53
Cancer numbers dropped 70% in six weeks on keto, versus 30% with chemo
1:20:43
Ketones protect muscle mass and improve mood during cancer treatment
1:22:55
Methylene Blue is an amazing brain energizer that supports mitochondrial function
1:24:47
Elevated kidney markers from creatine are likely false positives
1:27:01
Using GLP-1s for weight loss is like using chemotherapy to remove unwanted hair
1:28:58
Sustained ketone levels can naturally elevate GLP-1, reducing the need for expensive diabetes or weight-loss injections.
1:31:46
Insecurities can be reframed into power and drive relentless effort
1:43:36
Supreme Court erases 12 felonies after ruling attorney general abused power
1:49:39
Lasting change comes from small, consistent improvements, not overnight transformations.

Chapters

Intro
00:00
What Made You Who You Are Today?
02:16
Medicine 2.0 (Fixing) vs Medicine 3.0 (Preventing)
03:23
Predicting Chronic Illness 10 Years Before You Get It
04:17
Best Time to Eat
08:29
The Biggest Issue With Insulin Resistance
13:05
Scary Signs You Have Excess Insulin
14:27
Check for Skin Tags and Hairless Toes
18:35
My Patients Reversed Grey Hair on Keto
20:42
How to Measure Your Ketone Levels
21:40
Benefits of Being in Ketosis
23:15
Brain Differences on a Keto Diet vs Not
25:19
How Long Did It Take Annette to Achieve Ketosis?
27:38
Weightlifting on Keto
31:14
Improvements in Strength and Power
32:38
Can Keto Help Neurodegenerative Diseases?
34:16
Testing Steve's Ketones and Blood Sugar
38:39
Testing Dr. Boz's Ketones
41:06
How Cortisol Affects Metabolism
42:37
Jack's Ketone Levels
43:41
Do I Need to Fully Cut Carbs?
45:13
My Mum's Cancer Journey
46:27
12 Steps to Get Into a Consistent Ketogenic State
47:32
The Difference Between Men and Women on Keto
51:33
The Sardines Challenge to Start Keto
54:49
What Macros Do I Need to Get Into Ketosis?
57:31
Grocery List for a Keto Diet
58:07
What About Net Carbs?
59:15
Woman Who Ate Only Sardines for 30 Days
59:36
Will High Fat Affect the Gut Microbiome?
1:02:58
Will My Microbiome Be Diverse Enough on Keto?
1:06:56
The Role of Vitamin D
1:07:36
Lowering Insulin for Higher Vitamin D
1:08:33
Ads
1:09:49
Magnesium
1:10:43
Omega-3
1:11:43
Taking Exogenous Ketones
1:11:54
Exogenous Ketones vs Ketones Produced in the Body
1:12:24
Putting My Mum on Keto When She Was Dying of Cancer
1:14:32
Will This Reverse Cancer?
1:20:41
Methylene Blue
1:22:55
Do You Take Creatine?
1:24:47
GLP-1 Natural Alternatives
1:27:01
How to Stop Cravings
1:28:55
How to Keep People Motivated With Their Health Journey
1:31:45
Ads
1:32:57
They Tried to Sue Me for Fraud
1:35:08
What Helps You Find Inner Peace in Stressful Moments
1:46:54

Transcript

Dr. Annette Bosworth: Welcome to the Sardines Challenge. So the only thing on the menu for the next three days is sardines. I challenge you to try and eat three of those cans in a day. Because that's a hell of a tool to help you get into a ketogenic state....