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Where Is All the A.I.-Driven Scientific Progress?

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Where Is All the A.I.-Driven Scientific Progress?

Hard Fork

2025/12/26
Hard Fork

Hard Fork

2025/12/26
OverviewShownoteHighlightsTranscriptChaptersPins

Shownote

The leaders of the biggest A.I. labs argue that artificial intelligence will usher in a new era of scientific discovery, which will help us cure diseases and accelerate our ability to address the climate crisis. But what has A.I. actually done for science ...

Highlights

Artificial intelligence is increasingly being positioned as a transformative force in science, promising breakthroughs from medicine to climate solutions. In this conversation, a scientist at the intersection of AI and research offers a grounded perspective on what these tools can truly achieve today.
02:58
Sam Rodriques is more optimistic about AI's impact on science than some but skeptical of claims like curing all diseases in 5-10 years.
10:52
Kosmos identified a new mechanism related to type 2 diabetes.
18:40
Generative models can design proteins or antibodies from scratch
21:32
AI cannot shortcut the need for long-term clinical trials in medicine.
31:41
AlphaFold3 is likely underhyped given its potential impact on structural biology
36:32
AI agents may generate most high-quality scientific hypotheses by 2027

Chapters

Can AI Really Revolutionize Science — Or Is It Just Hype?
00:00
Meet Kosmos: The AI Scientist That Works Like a Postdoc
05:54
How AI Models Both Nature and the Way We Do Science
18:40
Can Machines Replicate Scientific Serendipity?
21:32
Why Knowing Isn’t Enough: AI’s Limits in Medicine
26:06
What’s Actually Working in AI-Driven Science Right Now?
34:07

Transcript

Kevin Roose: Cynthia Erivo is the best singer in the world. Casey Newton: She's incredible. Kevin Roose: I don't know what it is about her voice, but it brings me to tears every single fucking time I hear it. She has the most incredibly emotional voice. ...