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How to Control Your Metabolism by Thyroid & Growth Hormone

Huberman Lab

2021/04/26
Huberman Lab

Huberman Lab

2021/04/26

Shownote

This episode discusses metabolism and how our thyroid hormone and growth hormone control our metabolism. I also clarify that metabolism isn't just about burning energy, it’s about converting energy from different sources into fuels for building and repairing our tissues such as muscle, brain, and tendons and mobilizing energy from body fat storage. I discuss the role of iodine, selenium, and salt for thyroid health, and how specific exercise protocols, amino acids and temperature can dramatically shift levels of growth hormone release in waking and in sleep. I also describe the current landscape of prescription compounds, peptides and other factors for changing levels of thyroid and growth hormone, and some of their risks. Throughout the episode, mechanisms and tools grounded in specific mechanisms are discussed. Supplements from Thorne https://www.thorne.com/u/huberman Timestamps (00:00:00) Introduction (00:06:05) Thyroid & Growth Hormone (00:08:44) Food Shapes: Do They Matter? (00:11:43) Stevia: Naming & Impact (00:13:30) Metabolism 101: Your Brain the Furnace (00:17:33) Releasing Hormones From Your Brain, Stimulating Hormones from Your Pituitary (00:21:04) Thyroid Hormone’s Real Effects: Growth, Repair and Energy Consumption of Tissues (00:22:45) Iodine, L-Tyrosine & Selenium: The Trio Essential For Thyroid Function (00:26:05) How Much Iodine Do We Need? By Food, Supplement or Ocean Air (00:28:09) Selenium For Thyroid: Brazil Nuts & Other Valuable Sources (00:33:05) Selenium For Pregnancy, Prostate Cancer Risk, Acne (00:35:20) “Clean Eating” Downsides: Cruciferous Vegetables, Leeching Iodine (00:39:00) Other Benefits of Iodine: Reducing Inflammation (00:41:00) Why & How Increased Thyroid Increases Metabolism (00:42:12) What To Eat To Support Your Brain (00:43:00) Hyperthyroidism (Too Much) & Hypothyroidism (Too Little) (00:44:35) Menstruation: Thyroid Carbohydrate & Sugar Craving (00:45:33) Ketogenic Diet & Its Effects On Thyroid, Rebound Weight Gain (00:48:39) Growth Hormone: What, Why & How (00:51:18) Growth Hormone (GH) Changes Across The Lifespan & Risks of GH Therapy (00:53:40) How To Powerfully Increase Growth Hormone: Know The Natural Triggers (00:54:49) Not Eating Within 2hrs of Sleep: Keep Blood Glucose Low(ish) At Sleep (00:55:43) Delta Wave Brain Activity Is the Trigger For Growth Hormone Release (00:58:25) LOW Doses of Melatonin Supplementation For Increasing GH Release (01:01:00) Book: Altered Traits, Binaural Beats? Delta Waves Access (01:04:35) Specific Types & Duration of Exercise That Stimulate Growth Hormone & Warmups (01:08:40) Keeping Low Blood Glucose & Ensuring A Cool Down For Two Phase GH Release (01:10:36) Sex Differences For WHEN During Exercise Growth Hormone and IGF-1 Release Occurs: Males Have To Last Longer (01:14:10) Supplements That Increase Growth Hormone 100-400% (or more): Arginine, Ornithine (01:18:20) Arginine & Exercise Together Can Be Counter-Productive (01:19:50) L-Citrulline Better For Arginine Than Arginine Itself (?!); & Blood Pressure Caution (01:23:09) Growth Hormone Changes Across The Lifespan: No One Escapes (01:26:00) Heat (& Cold) for Triggering Extremely Large Increases In Growth Hormone (01:29:20) Specific Heat Protocols For Increasing Growth Hormone: Up To 16-Fold (?!) (01:34:30) 2021 (New) Study: Heat Increases GH, & Lowers Cortisol, No Effects On Testosterone, DHEA Or Prolactin (01:36:00) Prescription Growth Hormone, & Emerging Peptides Therapeutics, Secretagogues Etc. (01:42:25) Synthesis, Summary Of Actionable Steps For Increasing GH and Thyroid Hormone (01:44:00) Zero Cost & Other Ways to Support Our Podcast; & Thank You! Learn more about your ad choices. Visit megaphone.fm/adchoices

Highlights

This podcast delves into the intricacies of metabolism, focusing on the pivotal roles of thyroid and growth hormones. It explains how these hormones influence energy conversion, tissue repair, and overall health. The discussion covers essential nutrients like iodine, selenium, and L-tyrosine, along with lifestyle factors that can modulate hormone levels.
02:47
Recommended books include 'Live Wired', 'Lifespan', and 'Why We Sleep'.
06:10
Hormones impact development throughout life
11:43
Stevia is classified as a non-caloric sweetener, not artificial.
13:30
Two key hormones, thyroid and growth hormones, significantly impact metabolism.
17:36
Hypothalamus controls the release of thyroid-stimulating hormone via thyrotropin.
21:06
Thyroid hormone (T3) promotes metabolism and affects body composition.
22:47
Iodine combines with L-tyrosine to produce thyroid hormones T3 and T4.
26:08
Consulting a doctor is crucial for thyroid-related issues.
28:16
Selenium enables L-tyrosine and iodine interaction for thyroid hormone production.
33:07
Selenium helps reduce the risk of preeclampsia, prostate cancer, and acne.
35:25
Diets rich in meat but low in vegetables can lead to low iodine and reduced thyroid hormone.
39:03
Iodine supplementation reduces inflammation and supports thyroid health.
41:03
A healthy thyroid helps with injury recovery and supports brain function.
42:14
Healthy thyroid hormones are critical for brain metabolism[42:14]
43:03
Thyroid hormone levels can fluctuate during the menstrual cycle.
44:40
Experimenting with supplements or food intake for thyroid health
45:34
Low carb intake in ketogenic diets reduces T3 and T4 levels.
48:40
Growth hormone functions similarly to thyroid hormone.
51:25
Growth hormone decline impacts recovery and metabolism
53:42
To maintain or increase growth hormone levels, consult a doctor first.
54:50
Avoid eating too close to bedtime to optimize sleep
55:43
Deep sleep triggers the pituitary to release growth hormone.
58:28
Low-level melatonin aids delta wave sleep and growth hormone release
1:01:00
Certain meditations can mimic slow-wave sleep and promote growth hormone release.
1:07:53
High-intensity exercise close to muscle failure can increase growth hormone by 300-500%
1:08:40
Maintain blood glucose levels and avoid high-sugar intake to maximize growth hormone release
1:13:47
Women see maximum growth hormone and IGF-1 benefits in 30 minutes, while men need 60.
1:14:16
Arginine and ornithine can substantially increase growth hormone levels.
1:18:21
Taking arginine before exercise cancels out its effect on growth hormone.
1:19:52
L-citrulline can have powerful effects on vasodilation and potentially increase growth hormone levels.
1:23:17
Growth hormone decline is consistent between ages 30-40.
1:26:04
Growth hormone release starts in the hypothalamus and is influenced by temperature changes.
1:29:23
Heat exposure can increase growth hormone release 16-fold.
1:34:31
Heat exposure significantly decreases cortisol but not other hormones.
1:39:04
People inject Sermorelin before sleep to stimulate growth hormone release
1:42:28
Thyroid and growth hormones influence metabolism and tissue repair

Chapters

Introduction
00:00
Thyroid & Growth Hormone
06:05
Food Shapes: Do They Matter?
08:44
Stevia: Naming & Impact
11:43
Metabolism 101: Your Brain the Furnace
13:30
Releasing Hormones From Your Brain, Stimulating Hormones from Your Pituitary
17:33
Thyroid Hormone’s Real Effects: Growth, Repair and Energy Consumption of Tissues
21:04
Iodine, L-Tyrosine & Selenium: The Trio Essential For Thyroid Function
22:45
How Much Iodine Do We Need? By Food, Supplement or Ocean Air
26:05
Selenium For Thyroid: Brazil Nuts & Other Valuable Sources
28:09
Selenium For Pregnancy, Prostate Cancer Risk, Acne
33:05
“Clean Eating” Downsides: Cruciferous Vegetables, Leeching Iodine
35:20
Other Benefits of Iodine: Reducing Inflammation
39:00
Why & How Increased Thyroid Increases Metabolism
41:00
What To Eat To Support Your Brain
42:12
Hyperthyroidism (Too Much) & Hypothyroidism (Too Little)
43:00
Menstruation: Thyroid Carbohydrate & Sugar Craving
44:35
Ketogenic Diet & Its Effects On Thyroid, Rebound Weight Gain
45:33
Growth Hormone: What, Why & How
48:39
Growth Hormone (GH) Changes Across The Lifespan & Risks of GH Therapy
51:18
How To Powerfully Increase Growth Hormone: Know The Natural Triggers
53:40
Not Eating Within 2hrs of Sleep: Keep Blood Glucose Low(ish) At Sleep
54:49
Delta Wave Brain Activity Is the Trigger For Growth Hormone Release
55:43
LOW Doses of Melatonin Supplementation For Increasing GH Release
58:25
Book: Altered Traits, Binaural Beats? Delta Waves Access
1:01:00
Specific Types & Duration of Exercise That Stimulate Growth Hormone & Warmups
1:04:35
Keeping Low Blood Glucose & Ensuring A Cool Down For Two Phase GH Release
1:08:40
Sex Differences For WHEN During Exercise Growth Hormone and IGF-1 Release Occurs: Males Have To Last Longer
1:10:36
Supplements That Increase Growth Hormone 100-400% (or more): Arginine, Ornithine
1:14:10
Arginine & Exercise Together Can Be Counter-Productive
1:18:20
L-Citrulline Better For Arginine Than Arginine Itself (?!); & Blood Pressure Caution
1:19:50
Growth Hormone Changes Across The Lifespan: No One Escapes
1:23:09
Heat (& Cold) for Triggering Extremely Large Increases In Growth Hormone
1:26:00
Specific Heat Protocols For Increasing Growth Hormone: Up To 16-Fold (?!)
1:29:20
2021 (New) Study: Heat Increases GH, & Lowers Cortisol, No Effects On Testosterone, DHEA Or Prolactin
1:34:30
Prescription Growth Hormone, & Emerging Peptides Therapeutics, Secretagogues Etc.
1:36:00
Synthesis, Summary Of Actionable Steps For Increasing GH and Thyroid Hormone
1:42:25
Zero Cost & Other Ways to Support Our Podcast; & Thank You!
1:44:00

Transcript

Andrew Huberman: Welcome to the Huberman Lab Podcast, where we discuss science and science-based tools for everyday life. I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. This podcast is separate fr...