In this Huberman Lab Essentials [https://www.hubermanlab.com/essentials] episode, my guest is Dr. Chris Palmer, MD, a board-certified psychiatrist and Assistant Professor of Psychiatry at Harvard Medical School. We explain how nutrition and metabolism directly affect mental health, including the biological mechanisms underlying these effects. We also discuss how carbohydrate restriction, ketogenic diets and fasting can improve mood, energy, and, in some cases, treatment-resistant psychiatric conditions. Thank you to our sponsors AG1: https://drinkag1.com/huberman [https://drinkag1.com/huberman] Eight Sleep: https://eightsleep.com/huberman [https://eightsleep.com/huberman] BetterHelp: https://betterhelp.com/huberman [https://betterhelp.com/huberman] Timestamps (00:00:00) Chris Palmer (00:00:20) Personal Story, Nutrition & Mental Health (00:05:28) Treatment-Resistant Mental Disorders & Low-Carbohydrate Diet (00:07:32) Sponsor: Eight Sleep (00:08:51) Ketogenic Diet & Schizophrenia Success Story (00:12:20) Nutrition for Mental Disorders, Ketosis, Highly Processed Foods (00:15:13) Epilepsy & Ketogenic Diet, Fasting; Mitochondrial Benefits (00:21:14) Sponsor: BetterHelp (00:22:15) Mitochondria Functions, Mental Disorders (00:28:05) Mitophagy, Autophagy, Longevity & Calorie Restriction (00:33:12) Sponsor: AG1 (00:34:25) Carbohydrate Restriction, Depression Treatment (00:37:23) Acknowledgements Disclaimer & Disclosures [https://www.hubermanlab.com/disclaimer] Learn more about your ad choices. Visit megaphone.fm/adchoices [https://megaphone.fm/adchoices]