Using Red Light to Improve Metabolism & the Harmful Effects of LEDs | Dr. Glen Jeffery
Huberman Lab
2025/12/01
Using Red Light to Improve Metabolism & the Harmful Effects of LEDs | Dr. Glen Jeffery
Using Red Light to Improve Metabolism & the Harmful Effects of LEDs | Dr. Glen Jeffery

Huberman Lab
2025/12/01
Light is far more than a tool for visibility—it plays a fundamental role in regulating our biology at the cellular level. Emerging research reveals that specific wavelengths can either support or disrupt critical bodily functions, particularly through their effects on mitochondria, the energy powerhouses within our cells.
Long-wavelength light, such as red and near-infrared, enhances mitochondrial function by improving ATP production and reducing oxidative stress, with benefits extending to vision, blood glucose regulation, brain health, and aging. This type of light penetrates deeply into tissues—even through clothing and skull—enabling systemic effects from localized exposure. In contrast, excessive short-wavelength light from LEDs impairs mitochondrial activity, potentially contributing to metabolic dysfunction, eye strain, and reduced longevity. The balance between long and short wavelengths in lighting environments is crucial, as modern artificial lighting often lacks the full-spectrum quality of sunlight. Simple interventions like using incandescent or halogen bulbs, increasing daylight exposure, and applying targeted red light therapy can significantly improve metabolic and visual health, especially in older adults or those with mitochondrial dysfunction.
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Red light can improve skin and eyesight.
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Replacing cataracts with UV-blocking lenses reduces short-wavelength light exposure.
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Deadliest melanomas may occur without sun exposure.
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Improvements in mitochondrial function from long-wavelength light exposure correlate with water's absorption spectrum
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Long-wavelength light passes through multiple layers of clothing regardless of color
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Red light on the back reduces blood glucose spike by over 20% despite localized application.
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Mitochondria can be released from cells similarly to neurotransmitters, suggesting intercellular signaling roles.
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Red light passes through neonates' heads to measure mitochondrial function post-stroke
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A single 3-minute exposure to 670-nm light improves human color vision for up to five days
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One can't achieve the same biological effects with single-wavelength light as with sunlight.
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Mitochondria do more than just make energy
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Dim red light (1 mW/cm²) at 670 nm can improve vision in aging eyes
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Red light improved vision in control subjects despite no effect on macular degeneration patients
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Healthy cells transfer mitochondria to sick cells to aid recovery
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Excessive short-wavelength light from LEDs may be as harmful to human biology as asbestos exposure
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Mitochondria can distinguish between LED and incandescent light due to spectral differences
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LEDs claiming 670nm often deviate from advertised specs over time
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Color perception improved significantly with 40-watt incandescent desk lamps and remained improved months later
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Trees in urban areas reduce blood markers of stress.
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Excessive short-wavelength light can cause metabolic and visual dysfunctions
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Halogen lamps can be dimmed to save energy without affecting circadian rhythm.
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A child with mitochondrial disease showed significant improvement after red light therapy