People are running their own experiments with GLP-1s — with stunning results

Apple News In Conversation

3 HOURS AGO

Overview Shownote Highlights Transcript Chapters Pins

Shownote

GLP-1 drugs like Ozempic and Wegovy are being taken by millions of Americans. These medications have been approved for treating diabetes, obesity, and a small number of other chronic conditions. But even as experts are still learning how the drugs work, ma...

Highlights

This podcast explores the rapidly expanding use of GLP-1 drugs like Ozempic and Wegovy, moving beyond their approved uses for diabetes and obesity. It examines the phenomenon of people using these medications for a wide range of off-label conditions, creating what experts describe as a large-scale, uncontrolled experiment with unknown long-term consequences.

00:03

These drugs primarily affect the brain, not just the gut

05:53

65% of users want to stay on the drugs even if they stop working

15:00

Regulators lack systems to monitor informal data

21:00

We are learning in real time without long-term data.

Chapters

How GLP-1 Drugs Rewire the Brain, Not Just the Stomach

00:00

The Uncontrolled Experiment: Off-Label Use for Addiction, IBS, and More

05:53

Unknown Risks and the Gray Market: What Happens When Data Can't Keep Up?

15:00

A 600% Spike in Kids: Are We Experimenting on Developing Brains?

21:00

Transcript

Speaker 3: This is In Conversation from Apple News. I'm David Greene, in for Shumita Basu. Today, the GLP-1 experiment happening in real time. Millions of people in the U.S. Are taking GLP-1 medications right now, an estimated one in eight adults. You prob...