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Improve Focus With Behavioral Tools & Medication for ADHD | Dr. John Kruse

Huberman Lab

2025/03/10
Huberman Lab

Huberman Lab

2025/03/10

Shownote

My guest is Dr. John Kruse, M.D., Ph.D., a psychiatrist specializing in treating people with attention-deficit/hyperactivity disorder (ADHD). We discuss the many stimulant and nonstimulant ADHD medications available, covering both their potential benefits ...

Highlights

This podcast episode features Dr. John Kruse, a psychiatrist specializing in ADHD, who explores both medication and behavioral strategies for managing the condition. The discussion covers the rise in ADHD diagnoses, the role of genetics and environment, and the impact of modern life on attention, offering a comprehensive look at treatment options and lifestyle adjustments.
00:00
Circadian rhythm disruption is linked to ADHD.
02:11
Symptoms are common behaviors taken to an extreme.
08:54
COVID created a perfect storm for ADHD.
11:43
Temperature is crucial for sleep quality
14:26
ADHD brains are interest-driven rather than importance-driven
24:33
ADHD reduces lifespan by about 10 years
27:39
ADHD is a deficit of control over attention, not a lack of attention
33:46
Sleep is the most critical for ADHD
41:06
I've taken AG1 daily since 2012.
42:21
Quality sleep depends on both duration and consistency.
48:17
Insomnia is often the daytime arousal system failing to shut off
55:44
Cyclic sighing eliminated his nightly urination interruptions.
59:33
Medication reduces addiction risk by nearly 40%
1:07:40
Amphetamine-induced psychosis can persist for months
1:16:46
LMNT supports hydration and cognitive performance.
1:21:37
Serious risks are rare
1:32:20
Daily marijuana use is linked to lower motivation and energy.
1:33:54
Nicotine has a unique dual effect of arousal and anxiety reduction.
1:46:54
A natural 2:1 EPA to DHA ratio is likely better
1:52:56
Supports gut microbiome through varied diet and regular meal timing.
1:56:28
Categorize tasks as A, B, and C.
2:01:01
Use apps or lockboxes to restrict social media
2:02:38
Non-stimulant ADHD medications affect neurotransmitter availability within minutes to hours.
2:13:39
Modafinil may boost cognitive function more than motivation
2:25:36
Vyvanse's prodrug design limits abuse potential.
2:29:00
People with ADHD are inconsistently inconsistent in estimating time.
2:35:41
Subscribe, review, and check out my new book 'Protocols'.

Chapters

Dr. John Kruse
00:00
Attention-Deficit/Hyperactivity Disorder (ADHD)
02:11
Genetics & Environment; COVID Pandemic & ADHD Diagnoses
05:37
Sponsors: Eight Sleep & Joovv
11:43
ADHD, Interest & Careers
14:26
Social Media & Distractibility; ADHD & Lifespan Effect
20:40
Hyperfocus, Flow States
27:39
Tools: 4 Essential Behaviors for ADHD; Regular Meal Schedule
33:45
Sponsor: AG1
41:06
Tool: Regular Sleep Timing; Stimulants & Sleep
42:21
Insomnia; Tools: Bedtime Structure, Exercise, Phones, Breathing
48:06
Nighttime Waking Up; Cyclic Sighing
52:30
Exercise; Addiction, Risk, Kids & Stimulants; Catecholamines & Focus
56:35
Ritalin, Stimulants, Amphetamines; Amphetamine-Induced Psychosis & Risks
1:04:32
Sponsor: LMNT
1:16:46
Adult ADHD & Medications; Stimulants & Cardiovascular Risk?
1:18:03
Adult ADHD Medication Choices, Psychosis, Cannabis
1:26:06
ADHD Symptoms, Nicotine; Caffeine, Energy Drinks, L-Theanine
1:33:49
Fish Oil, Cardiac Effects & ADHD, Tool: Fish Oil Dose, EPA vs DHA
1:43:28
Sponsor: Mateina
1:49:38
Gut Microbiome
1:51:04
ADHD & Cognitive Behavioral Therapy (CBT), Tool: Task List System
1:52:56
Video Games, Neurofeedback, ADHD Benefit?, Tool: Technology Restriction
1:57:52
Guanfacine, Clonidine, Hypertension, Effects & Timeframe
2:02:26
Modafinil, History & Forms, Dependence
2:10:13
Drug Holidays; Short- vs Long-Acting Drugs, Addiction, Vyvanse
2:19:02
Time Perception, ADHD, Circadian Rhythm Disruption, Phototherapy
2:28:56
Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter
2:35:39

Transcript

Andrew Huberman: Welcome to the Huberman Lab Podcast, where we discuss science and science-based tools for everyday life. I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. My guest today is Dr. John ...